We need to overcome "the terror of voidness" to finish our own great goal.
The loneliness comes when nobody knows about our work.
The voidness comes when the loneliness continues for a long time.
And then finally,
it turns to the lethargy.
The lethargy ends up with the terror and bipolar disorder.
Most of time, however, we fails to overcome the ordeal.
As a result, we give up the great goal.
If we cannot overcome it,
we will never achieve our goal.